Acute acalculous cholecystitis: an unusual presenting feature of Churg-Strauss vasculitis.

of Churg–Strauss vasculitis (CSV) is 2.5 per 100 000 people per year. It is characterized by pulmonary and systemic necrotizing vasculitis, vascular or extravascular granuloma, eosinophilia and tissue infiltration by eosinophils, and nonspecific elevation in the immunoglobulin E level. It is also found in those with asthma and allergic rhinitis or sinonasal polyposis. Coarse granular and perinuclear antineutrophil cytoplasmic antibodies can be detected in 38%–50% of patients. Pathologically, CSV is characterized by small-vessel angiitis and extravascular necrotizing granulomas, usually containing eosinophilic infiltrates. We describe an unusual presentation of CSV: acute acalculous cholecystitis.